Posts Tagged ‘Aging’

140+ Reasons Why Sugar Is Ruining Your Health

Sunday, November 28th, 2010

The following list was written by Nancy Appleton, Ph.D. (visit her very informative website www.nancyappleton.com), the author of the book Lick The Sugar Habit.

In addition to throwing off the body’s homeostasis, excess sugar may result in a number of other significant consequences. The following is a listing of some of sugar’s metabolic consequences from a variety of medical journals and other scientific publications.

141 Reasons Sugar Ruins Your Health

(Just Kidding, it’s 143)

By Nancy Appleton PhD & G.N. Jacobs

Excerpted from Suicide by Sugar

Used with permission

1. Sugar can suppress your immune system.

2. Sugar upsets the mineral relationships in the body.

3. Sugar can cause juvenile delinquency in children.

4. Sugar eaten during pregnancy and lactation can influence muscle force production in offspring, which can affect an individual’s ability to exercise.

5. Sugar in soda, when consumed by children, results in the children drinking less milk.

6. Sugar can elevate glucose and insulin responses and return them to fasting levels slower in oral contraceptive users.

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The FASEB Journal 2006 – Towards a “free radical theory of graying” …

Wednesday, October 27th, 2010

The FASEB Journal 2006;20:1567-1569.

Towards a “free radical theory of graying”: melanocyte apoptosis in the aging human hair follicle is an indicator of oxidative stress induced tissue damage

Petra Clara Arck†,1, Rupert Overall*,1, Katharina Spatz*, Christiane Liezman*, Bori Handjiski†, Burghard F. Klapp‡, Mark A. Birch-Machin§ and Eva Milena Johanne Peters*,1

* Cutaneous Neuroimmunology, Biomedical Research Center, University Medicine Charité, Virchow and Mitte Campus;

† Psychoneuroimmunology, Biomedical Research Center, University Medicine Charité, Virchow Campus; and

‡ Internal Medicine, Psychosomatics, University Medicine Charité, Mitte Campus, Humboldt-University of Berlin, Berlin, Germany; and

§ Dermatology, Medical School, University of Newcastle, UK

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1Correspondence: Biomedical Research Center, Rm. Nr. 2.0549, University Medicine Charité, Virchow Campus, Humboldt University of Berlin, Augustenburger Platz 1, Berlin 13353, Germany. E-mail: eva.peters@charite.de or frl_peters@yahoo.com

ABSTRACT

Oxidative stress is generated by a multitude of environmental and endogenous challenges such as radiation, inflammation, or psychoemotional stress. It also speeds the aging process. Graying is a prominent but little understood feature of aging.

Intriguingly, the continuous melanin synthesis in the growing (anagen) hair follicle generates high oxidative stress. We therefore hypothesize that hair bulb melanocytes are especially susceptible to free radical-induced aging. To test this hypothesis, we subjected human scalp skin anagen hair follicles from graying individuals to macroscopic and immunohistomorphometric analysis and organ culture. We found evidence of melanocyte apoptosis and increased oxidative stress in the pigmentary unit of graying hair follicles.

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