Posts Tagged ‘Botox’

Study: Treatment effects of intradermal botulinum toxin type A injection on alopecia areata

Sunday, September 18th, 2011

-:: This Abstract is posted here for posterity and archival purposes only ::-

Dermatol Surg. 2010 Dec;36 Suppl 4:2175-81. doi: 10.1111/j.1524-4725.2010.01709.x.
Treatment effects of intradermal botulinum toxin type A injection on alopecia areata.
Cho HR, Lew BL, Lew H, Sim WY.
Source

Department of Dermatology, College of Medicine, Kyunghee University, Seoul, Korea.
Abstract
BACKGROUND:

There are several different treatment options for alopecia areata (AA); Botulinum toxin type A (BTXA) can induce changes in neurotransmitter levels, directly or via neuroimmunologic mechanisms. Therefore it is thought that BTXA may influence cytokines that are responsible for hair growth arrest that characterizes AA.
OBJECTIVES:

To prospectively examine the safety and efficacy of BTXA injections for the treatment of patients with AA of the scalp.
METHODS AND MATERIALS:

Seven patients with AA received 10 U of BTXA intradermal injections on each site three times. Subjects were classified according to the extent of scalp hair loss into Severity of Alopecia Tool subclasses.
RESULTS:

Two patients had one patch of AA; the remaining patients had total or universal type AA. One patient dropped out of the study after experiencing spontaneous recovery from her AA. One patient reported aggravation of her AA after BTXA injections. The remaining patients’ AA did not change after BTXA injections.
CONCLUSION:

Our results suggest that BTXA injection cannot be used as an alternative treatment for recalcitrant AA. Nevertheless, future studies concerning the treatment efficacy of BTXA for mild to moderate AA are warranted.

© 2010 by the American Society for Dermatologic Surgery, Inc.

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Study: Treatment of Male Pattern Baldness with Botulinum Toxin: A Pilot Study

Sunday, September 18th, 2011

Comment by Ethan:

This study is important because it reminds us that T conversion to DHT occurs in low oxygen environments, that the muscles (or anything) that constricts blood flow also reduces the availability of Oxygen in the scalp and dermal papilla.  Thus, relaxing these muscles, via botox (something I would not recommend since botox is a toxin), other approaches to relax the muscles and/or increase circulation and Oxygen levels include: various types of scalp massages, acupuncture, diet and nutrition, reducing inflammation, relaxation exercises etc is helpful to men with hair loss resulting from a genetic sensitivity to DHT.

 

 -:: This Abstract is posted here for posterity and archival purposes only ::-

Treatment of Male Pattern Baldness with Botulinum Toxin: A Pilot Study

Freund, Brian J. D.D.S., M.D.; Schwartz, Marvin D.D.S., M.Sc.

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Plastic and Reconstructive Surgery . 126(5):246e-248e, November 2010.

doi: 10.1097/PRS.0b013e3181ef816d

Author Information

Crown Institute; Pickering, Ontario, Canada

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